Seroprevalence of antibodies against SARS-Cov-2 among adults from a municipality in the Buenos Aires suburbs, República Argentina

The objective of this study was to determine the prevalence of anti-bodies against SARS-CoV-2. Between November twenty-one and December twelve of two thousand and twenty year, a cross-sectional study was carried out in 1182 samples from residents of a Buenos Aires town in the Province of Buenos Aire...

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Detalles Bibliográficos
Autores: Consiglio, Ezequiel; Freytes, Carlos; Facal, Leandro; Dus Santos, María José; Radgtky Caffera, Magdalena; Mozgovoj, Marina; Robledo, Iris Celeste; Pilloff, Marcela; Fernandez Souto, Adriana; Pedrosa, Juan
Tipo de documento: Artículo
Estado:Published version
Fecha de publicación:2023
País:Costa Rica
Institución:UCR
Repositorio:Portal de Revistas UCR
Lenguaje:Español
OAI Identifier:oai:portal.ucr.ac.cr:article/53436
Acceso en línea:https://revistas.ucr.ac.cr/index.php/psm/article/view/53436
Nivel de acceso:Acceso abierto
Palabra clave:COVID-19
seropravelence
cross sectional study
seroprevalencia
estudio transversal
Descripción
Sumario:The objective of this study was to determine the prevalence of anti-bodies against SARS-CoV-2. Between November twenty-one and December twelve of two thousand and twenty year, a cross-sectional study was carried out in 1182 samples from residents of a Buenos Aires town in the Province of Buenos Aires, Argentina. IgG was measured by ELISA in samples obtained by acupressure. The global prevalence was 12.2 % (n = 144; 95 % CI: 10.3 - 14.0) with a ratio of 1: 3.8, between cumulative incidence and observational values. Prevalence in women and men were 13.0 % (95 % CI: 10.2 - 15.7) and 10.5 % (95 % CI: 7.6 - 13.3), respectively (p = 0.21). By age, the observed values were: 17.8 % (95 % CI: 12.0 - 23.6) in 18 and 30 years old group; 12.2 % (95 % CI: 9.3 - 15.1) in 31 to 60 years old group, 9.9 % (95 % CI: 6.9 - 13.9) in people over 61 years old (p = 0.02). According the socioeconomic tertiles (for Unsatisfied Basic Needs) the prevalence values were 7.7 % (95 % CI: 4.7 - 10.7) for Tertile I (best tertile), 12.5 % (95 % CI: 8.7 - 16.4) for Tertile II, and 15.2 % (95 % CI: 11.6 - 18.8) for Tertile III (p = 0.002). There were also differences between the neighbourhoods and between self-reported clinical variables. Specific IgM antibodies were detected in 12 samples, which represented 1% of the total. Seroprevalence studies provide useful information that can be apllied to fit modeling.