Epigenetic regulation in neural crest development
The neural crest is a migratory and multipotent cell population that plays a crucial role in many aspects of embryonic development. In all vertebrate embryos, these cells emerge from the dorsal neural tube then migrate long distances to different regions of the body, where they contribute to formati...
| Authors: | ; ; |
|---|---|
| Format: | Article |
| Status: | Published version |
| Publication date: | 2014 |
| Country: | Argentina |
| Institution: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repository: | CONICET Digital (CONICET) |
| Language: | English |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/33272 |
| Online Access: | http://hdl.handle.net/11336/33272 |
| Access Level: | Open access |
| Keyword: | Epigenetic Neural Crest Development https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 |
| _version_ | 1878403967068667904 |
|---|---|
| author | Hu, Na |
| author2 | Strobl Mazulla, Pablo Hernan Bronner, Marieanne E. |
| author2_role | author author |
| author_browse | Bronner, Marieanne E. Hu, Na Strobl Mazulla, Pablo Hernan |
| author_facet | Hu, Na Strobl Mazulla, Pablo Hernan Bronner, Marieanne E. |
| author_role | author |
| collection | CONICET Digital (CONICET) |
| description | The neural crest is a migratory and multipotent cell population that plays a crucial role in many aspects of embryonic development. In all vertebrate embryos, these cells emerge from the dorsal neural tube then migrate long distances to different regions of the body, where they contribute to formation of many cell types and structures. These include much of the peripheral nervous system, craniofacial skeleton, smooth muscle, and pigmentation of the skin. The best-studied regulatory events guiding neural crest development are mediated by transcription factors and signaling molecules. In recent years, however, growing evidence supports an important role for epigenetic regulation as an additional mechanism for controlling the timing and level of gene expression at different stages of neural crest development. Here, we summarize the process of neural crest formation, with focus on the role of epigenetic regulation in neural crest specification, migration, and differentiation as well as in neural crest related birth defects and diseases. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | AR_e1e8423e8a480aea5eb0a3bcf68de00a |
| identifier_str_mv | Hu, Na; Strobl Mazulla, Pablo Hernan; Bronner, Marieanne E.; Epigenetic regulation in neural crest development; Academic Press Inc Elsevier Science; Developmental Biology; 396; 2; 11-2014; 159-168 0012-1606 CONICET Digital CONICET |
| institution | Consejo Nacional de Investigaciones Científicas y Técnicas |
| instname_str | Consejo Nacional de Investigaciones Científicas y Técnicas |
| language | eng |
| network_acronym_str | AR |
| network_name_str | Argentina |
| oai_identifier_str | oai:ri.conicet.gov.ar:11336/33272 |
| publishDate | 2014 |
| publishDateSort | 2014 |
| publisher | Academic Press Inc Elsevier Science |
| publisherStr | Academic Press Inc Elsevier Science |
| reponame_str | CONICET Digital (CONICET) |
| spelling | Epigenetic regulation in neural crest development Hu, Na Strobl Mazulla, Pablo Hernan Bronner, Marieanne E. Epigenetic Neural Crest Development https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 The neural crest is a migratory and multipotent cell population that plays a crucial role in many aspects of embryonic development. In all vertebrate embryos, these cells emerge from the dorsal neural tube then migrate long distances to different regions of the body, where they contribute to formation of many cell types and structures. These include much of the peripheral nervous system, craniofacial skeleton, smooth muscle, and pigmentation of the skin. The best-studied regulatory events guiding neural crest development are mediated by transcription factors and signaling molecules. In recent years, however, growing evidence supports an important role for epigenetic regulation as an additional mechanism for controlling the timing and level of gene expression at different stages of neural crest development. Here, we summarize the process of neural crest formation, with focus on the role of epigenetic regulation in neural crest specification, migration, and differentiation as well as in neural crest related birth defects and diseases. Fil: Hu, Na. California Institute of Technology. Pasadena; Estados Unidos Fil: Strobl Mazulla, Pablo Hernan. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Instituto de Investigaciones Biotecnológicas "Dr. Raúl Alfonsín" (sede Chascomús). Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas. Instituto de Investigaciones Biotecnológicas "Dr. Raúl Alfonsín" (sede Chascomús); Argentina Fil: Bronner, Marieanne E.. California Institute of Technology. Pasadena; Estados Unidos Academic Press Inc Elsevier Science http://hdl.handle.net/11336/33272 Hu, Na; Strobl Mazulla, Pablo Hernan; Bronner, Marieanne E.; Epigenetic regulation in neural crest development; Academic Press Inc Elsevier Science; Developmental Biology; 396; 2; 11-2014; 159-168 0012-1606 CONICET Digital CONICET |
| spellingShingle | Epigenetic regulation in neural crest development Hu, Na Epigenetic Neural Crest Development https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 |
| status_str | publishedVersion |
| title | Epigenetic regulation in neural crest development |
| title_full | Epigenetic regulation in neural crest development |
| title_fullStr | Epigenetic regulation in neural crest development |
| title_full_unstemmed | Epigenetic regulation in neural crest development |
| title_short | Epigenetic regulation in neural crest development |
| title_sort | Epigenetic regulation in neural crest development |
| topic | Epigenetic Neural Crest Development https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 |
| topic_facet | Epigenetic Neural Crest Development https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 |
| url | http://hdl.handle.net/11336/33272 |