Sex Differences in insulin resistance in GABAB1 knock out mice

We have previously demonstrated that the absence of functional GABA B receptors (GABABRs) disturbs glucose homeostasis in GABAB1KO mice. The aim of this work was to extend our studies of these alterations in GABAB1KO mice and investigate the sexual differences therein.

Authors: Bonaventura, Maria Marta; Rodriguez, D.; Ferreira, M. L.; Crivello, Martin; Repetto, E. M.; Bettler, B.; Libertun, Carlos; Lux, Victoria Adela R.
Format: Article
Status:Published version
Publication date:2012
Country:Argentina
Institution:Consejo Nacional de Investigaciones Científicas y Técnicas
Repository:CONICET Digital (CONICET)
Language:English
OAI Identifier:oai:ri.conicet.gov.ar:11336/9728
Online Access:http://hdl.handle.net/11336/9728
Access Level:Open access
Keyword:DIABETES
INSULIN SIGNALIG
GABAB RECEPTORS
AKT ACTIVATION
NPY EXPRESSION
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
Summary:We have previously demonstrated that the absence of functional GABA B receptors (GABABRs) disturbs glucose homeostasis in GABAB1KO mice. The aim of this work was to extend our studies of these alterations in GABAB1KO mice and investigate the sexual differences therein.

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