Efficient Routes to Racemic and Enantiomerically Pure (S)-BINOL Diesters

A systematic study for esterification procedures to the synthesis of BINOL diesters is described. Reaction conditions with TFAA and 85% H3PO4 were selected as the best procedure to prepare enantiomerically pure (S)-BINOL diesters VIII to XI with almost quantitative yields and very low reaction times...

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Autores: Costantino, Andrea Rosana; Ocampo, Romina Andrea; Montiel Schneider, María Gabriela; Fernández, Gustavo Alejandro; Koll, Liliana Cristina; Mandolesi, Sandra Delia
Tipo de documento: Artículo
Estado:Published version
Fecha de publicación:2013
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Lenguaje:Inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/101840
Acceso en línea:http://hdl.handle.net/11336/101840
Nivel de acceso:Acceso abierto
Palabra clave:DIOLS
ESTERIFICATION
PHASE-TRANSFER CATALYSIS
DIESTERS
BINOL
C2 SYMETRY
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Sumario:A systematic study for esterification procedures to the synthesis of BINOL diesters is described. Reaction conditions with TFAA and 85% H3PO4 were selected as the best procedure to prepare enantiomerically pure (S)-BINOL diesters VIII to XI with almost quantitative yields and very low reaction times.

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