Exploring Autophagy In Drosophila

Autophagy is a catabolic process in eukaryotic cells promoting bulk or selective degradation of cellular components within lysosomes. In recent decades, several model systems were utilized to dissect the molecular machinery of autophagy and to identify the impact of this cellular "self-eating" proce...

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Bibliographic Details
Authors: Lörincz, Péter; Mauvezin, Caroline; Juhász, Gábor
Format: Article
Status:Published version
Publication date:2017
Country:España
Institution:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repository:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/124266
Online Access:https://hdl.handle.net/2445/124266
Access Level:Open access
Keyword:Autofàgia
Drosòfila melanogaster
Autophagy
Drosophila melanogaster
Description
Summary:Autophagy is a catabolic process in eukaryotic cells promoting bulk or selective degradation of cellular components within lysosomes. In recent decades, several model systems were utilized to dissect the molecular machinery of autophagy and to identify the impact of this cellular "self-eating" process on various physiological and pathological processes. Here we briefly discuss the advantages and limitations of using the fruit fly Drosophila melanogaster, a popular model in cell and developmental biology, to apprehend the main pathway of autophagy in a complete animal.