The association of prior paracetamol intake with outcome of very old intensive care patients with COVID-19: results from an international prospective multicentre trial.

In the early COVID-19 pandemic concerns about the correct choice of analgesics in patients with COVID-19 were raised. Little data was available on potential usefulness or harmfulness of prescription free analgesics, such as paracetamol. This international multicentre study addresses that lack of evi...

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Authors: Baldia PH; Wernly B; Flaatten H; Fjølner J; Artigas A; Pinto BB; Schefold JC; Kelm M; Beil M; Bruno RR; Binnebößel S; Wolff G; Erkens R; Sigal S; van Heerden PV; Szczeklik W; Elhadi M; Joannidis M; Oeyen S; Marsh B; Andersen FH; Moreno R; Leaver S; De Lange DW; Guidet B; Jung C; COVIP study group
Format: Article
Status:Published version
Publication date:2022
Country:España
Institution:Institut d'Investigació i Innovació Parc Taulí (I3PT)
Repository:r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí
OAI Identifier:oai:i3pt.fundanetsuite.com:p1553
Online Access:https://i3pt.portalinvestigacion.com/publicaciones/1553
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85144811790&doi=10.1186%2fs12877-022-03709-w&partnerID=40&md5=65a230589db7c2362ec9634e583186bb
Access Level:Open access
Keyword:Analgesics, COVID-19, Frailty, ICU, Paracetamol
Summary:In the early COVID-19 pandemic concerns about the correct choice of analgesics in patients with COVID-19 were raised. Little data was available on potential usefulness or harmfulness of prescription free analgesics, such as paracetamol. This international multicentre study addresses that lack of evidence regarding the usefulness or potential harm of paracetamol intake prior to ICU admission in a setting of COVID-19 disease within a large, prospectively enrolled cohort of critically ill and frail intensive care unit (ICU) patients.

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