Down-regulation of autophagy proteins is associated with higher mTOR expression in the placenta of pregnant women with preeclampsia

Autophagy is a lysosomal degradation pathway that removes protein aggregates and damaged organelles maintaining cellular integrity. It seems to be essential for cell survival during stress, starvation, hypoxia, and consequently to the placenta implantation and development. Preeclampsia (PE) is a mul...

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Detalles Bibliográficos
Autores: Weel, I. C. [UNESP]; Ribeiro, V. R. [UNESP]; Romão-Veiga, M. [UNESP]; Fioratti, E. G. [UNESP]; Peraçoli, J. C. [UNESP]; Peraçoli, M. T.S. [UNESP]
Tipo de documento: Artículo
Estado:Published version
Fecha de publicación:2022
País:Brasil
Institución:UNESP
Repositorio:Repositório Institucional da UNESP
Lenguaje:Inglés
OAI Identifier:oai:repositorio.unesp.br:11449/248182
Acceso en línea:http://dx.doi.org/10.1590/1414-431X2022e12283
http://hdl.handle.net/11449/248182
Nivel de acceso:Acceso abierto
Palabra clave:Autophagy
Beclin-1
LC3
mTOR
Placenta
Preeclampsia